SYNCREST ?
Know SynCrest.
Three "S"s that represent the characteristics of SynCrest
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Synergy
Pursuing the possibilities of middle-molecular drugs with an attitude of “Creating Together” by fusing various technologies.
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Speedy
Realizing the synthesis of compounds with short delivery times by rapid and precision reaction control using in-line measurement technologies.
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Satisfaction
Pursuing customer satisfaction by responding to various needs in drug discovery research.
Synergy
Pursuing the possibilities of middle-molecular drugs with an attitude of “Creating Together” by fusing various technologies.
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Synergy01
Your Partner Who Stays Close to
Customers and Creates TogetherWe derive the best solutions for customers by fusing new technologies with various synergistic effects while sharing requests and visions with customers; and we are a partner who faces the challenges confronting us and creates together – This is the basic stance that SynCrest considers most important.
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Synergy02
Fusion of Two World-Class
Cutting-edge TechnologiesThe greatest strength of SynCrest lies in its continuous flow synthesis technology integrated with in-line measurements that is combined with a flow synthesis method that has been developed based on organic synthesis technology evolved over many years of pharmaceutical manufacturing and non-invasive real-time monitoring technology. The combination of the world’s most advanced flow synthesis technology and world-class measurement/control technology has made it possible to synthesize and produce middle-molecular compounds that could not be realized by conventional methods.
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Synergy03
Collaboration between Two Centers Engaged
in R&D and Manufacturing ControlWe have a system that enables the implementation of R&D support and the consistent production of middle-molecular raw materials, intermediates, and active pharmaceutical ingredients (APIs) through seamless cooperation between two centers, an R&D center in the Shonan Health Innovation Park, Fujisawa, Kanagawa Prefecture, and the Multi-Purpose Plant, which is a center for our manufacturing and quality control divisions in Naruto, Tokushima Prefecture.
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Synergy04
CRDMO – Consistent Processing of
Raw Materials to APIsSynCrest has developed a unique CRDMO (contract research, development, and manufacturing organization) model enables everything from research to the production phase to be handled consistently, particularly in regards to the raw materials for middle-molecular drugs, intermediates, and APIs. SynCrest responds to the diverse needs of customers based on the world’s most advanced continuous flow synthesis technology integrated with in-line measurements.
Speedy
Realizing the synthesis of compounds with short delivery times by rapid and precision reaction control using in-line measurement technologies.
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Speedy01
Speedy Precision
Measurement TechnologiesOne of the important characteristics of continuous flow synthesis technologies integrated with in-line measurements is the advanced measurement technology that supports speedy precision control of temperatures, reagent mix ratios, high-speed mixing of reagents, etc. in the synthesis process. The control of these parameters leads to various advantages, such as shorter reaction times, reduced impurities, improved yield, and high reproducibility.
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Speedy02
Both Short Delivery Time and Safety Can be
Achieved with the Flow Synthesis MethodThe conventional organic synthesis method (batch synthesis method) requires the construction of a large plant to perform a large amount of synthesis at a time. It is also necessary to reconsider reaction conditions every time production is scaled up. On the other hand, the flow synthesis method enables successive reactions, as well as easy scale-up of production by extending the liquid feeding time. In addition, since it can also cause reactions in a fully closed system, it makes it feasible to safely realize reactions that previously caused safety concerns in the synthesis process.
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Speedy03
Cutting-edge Flow Synthesis Technology
Enables Short Delivery TimeSynCrest’s continuous flow synthesis technologies integrated with in-line measurements incorporate world-class sensing technology and it is possible to immediately detect abnormalities in synthetic reactions and take corrective action. Our integrated synthesis to crystallization process system enables short delivery time.
Satisfaction
Pursuing customer satisfaction by responding to various needs in drug discovery research.
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Satisfaction01
Flexible Support for Various
Compound Synthesis RequestsSynCrest responds flexibly to customer requests for the production of general middle-molecular raw materials, intermediates, APIs, and other compounds unlisted in the CAS registry/literature, based on our experience and knowledge of organic synthesis that we have developed over many years.
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Satisfaction02
From Trial/Study Scale
to Production ScaleSynCrest’s continuous flow synthesis technologies integrated with in-line measurements enables the easy scale-up of production by extending the liquid feeding time for successive synthetic reactions. This enables rapid transition from laboratory scale to production scale while minimizing scale-up challenges.
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Satisfaction03
High-Quality, Low-Cost
On-Demand ProductionThe optimization of synthesis conditions and real-time monitoring of synthetic reactions brought about by SynCrest’s flow synthesis and sensing technologies have led to the realization of high-quality production, such as improved yields and reduced impurities, as well as low-cost production through automation. SynCrest can handle requests for on-demand, high-purity production of APIs, API intermediates, and raw materials with which various types of middle molecular-based chemical synthesis can be performed.
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Satisfaction04
Environmentally Friendly, Space-Saving,
and Energy-Saving Development EquipmentSynCrest’s continuous flow synthesis technologies integrated with in-line measurements removes the need for large-scale plant construction for the conventional synthesis of drug-related compounds. We have realized development that leads to an environment-friendly future by designing space-saving and energy-saving efficient systems that meet the needs of our time.