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Results of joint research with associate professor Koichi Matsumoto of Kindai University published in Electrochemistry journal
In collaboration with Associate Professor Koichi Matsumoto of the Department of Science, Graduate School of Science and Engineering, Kindai University, Dr. Xu Pengyu and Dr. Shin Yoneyama of SynCrest Inc. succeeded in developing a new cyanation reaction for benzothiazoles using electrical energy.
The results were published in the Electrochemistry journal (Impact Factor 2.7).
Electrochemical Cyanation of Benzothiazole Derivatives
(DOI: https://doi.org/10.5796/electrochemistry.24-00133)
Benzothiazole and its derivatives are chemical substances that serve as basic skeletons in pharmaceuticals and functional materials. Improvements in synthetic methods are expected to be developed into a wide range of fields, including pharmaceuticals.
In this study, we established a synthetic method capable of efficiently introducing cyano groups by passing an electric current through benzothiazoles and an easily handled TMSCN (trimethylsilyl cyanide) as a cyanation source.
This synthesis method makes it possible to significantly reduce the environmental impact by using electrochemistry, and is expected to lead to the environmentally friendly development facilities that SynCrest aims for.